What Is Hyaluronidase and How Does It Work to Dissolve Lip Fillers?
- Iuliana Molac
- Apr 13
- 2 min read
Updated: Jun 8
If you’ve ever wondered how lip fillers can be safely reversed, the answer lies in an enzyme called hyaluronidase. This naturally occurring substance plays a crucial role in dissolving unwanted hyaluronic acid-based fillers — offering peace of mind and flexibility in your aesthetic journey.
Let’s break it down simply.
What Is Hyaluronidase?
Hyaluronidase is an enzyme that breaks down hyaluronic acid (HA) — the same substance used in most modern lip fillers. Because HA is naturally found in the body, this enzyme can safely dissolve it without harming your own tissue.
Clinics use a medical-grade version of hyaluronidase, specifically designed for cosmetic use. It works quickly and is especially helpful for correcting uneven results, filler migration, or simply reversing the treatment if your preferences change.
How Does It Actually Work?
When hyaluronidase is injected into the area where the filler sits, it breaks the bonds holding the HA gel together. The product then becomes soft, breaks down, and is absorbed by your body.
⏱️ Most people see visible results within 24–48 hours.
💬 Some even notice changes immediately after treatment, especially when correcting small areas.
For a detailed look at the step-by-step process, visit:👉 How to Dissolve Lip Fillers: Safe & Effective Ways to Reverse Results
Is It Safe?
Yes — when performed by an experienced aesthetic professional. Side effects like swelling or bruising can occur, but they’re usually mild and short-lived. The key is choosing a trusted, qualified injector who understands facial anatomy and proper technique.
When Is Hyaluronidase Recommended?
This treatment may be suggested if:
You’ve had overfilled or migrated filler
Results look uneven or lumpy
You’ve changed your mind about the treatment
There’s a medical complication that requires reversal
It’s a highly effective solution that gives you back control over your look — and your confidence.
FAQs
Can hyaluronidase dissolve all types of lip fillers?
Hyaluronidase is specifically designed to dissolve lip fillers made from hyaluronic acid (HA) — the most common type used in modern aesthetics. If your filler is HA-based, this enzyme can safely break it down. However, it won’t work on permanent or non-HA fillers, so it’s essential to check with your injector to confirm what type of product was used.
How long does it take for hyaluronidase to fully dissolve lip fillers?
You’ll usually notice results within 24 to 48 hours after the injection. In some cases, it may take up to a week for the full effect to develop, especially if a larger amount of filler needs to be dissolved. Everyone’s body metabolizes the product slightly differently, so your practitioner will guide you on what to expect.
Final Thoughts
Hyaluronidase is a powerful tool in aesthetic medicine — offering a safe, effective way to correct or reverse lip filler results when needed. Whether you’re unsure about your current results or just want more flexibility, this enzyme-based treatment gives you options.
Still have questions about dissolving lip fillers?Let’s talk. Book your personalised consultation today and feel confident about every step of your treatment journey.


